Lifestyle

New mouth spray could benefit patients with painful genetic skin condition

A new spray for treating severely painful blisters, mouth ulceration and oral scarring in patients with a rare genetic skin condition is being developed by researchers at the University of Birmingham. The spray is designed for patients with Epidermolysis Bullosa (EB), a condition that causes the skin to blister and tear at the slightest touch. […]

Lifestyle

Severe form of inflammatory bowel disease linked to a strain of mouth bacteria

Severe ulcerative colitis—a form of inflammatory bowel disease (IBD)—has been linked to a newly-discovered strain of oral bacteria, a study led by UNSW Sydney has found. Scientists have discovered a molecule called ‘pSma1’ in bacterial cell samples from people with severe ulcerative colitis. The molecule was found in some strains of the bacterium Campylobacter concisus […]

Lifestyle

How allergens trigger itching: Finding points to new targets for allergy drug development

A key step in the immune system’s response to allergens has been uncovered by researchers at Massachusetts General Hospital (MGH). They have shown that a neuropeptide called Substance P is released by certain neurons in the skin when they detect allergens, and that this substance is essential in the development of allergen-induced immune responses. This […]

Lifestyle

Higher stillbirth risk for mothers experiencing deprivation, unemployment, stress and domestic abuse in pregnancy

Mothers who experience psychological stress and domestic abuse are more likely to have stillborn babies—but attending more antenatal care appointments than UK guidelines currently dictate can reduce that risk, according to a new study from Tommy’s Manchester Research Centre at The University of Manchester. In the UK, one in every 250 pregnancies ends in stillbirth—when […]

Lifestyle

Motivation to seek cocaine is driven by elegant cellular communication

In the October 28, 2020 issue of the Journal of Neuroscience, researchers from the Medical University of South Carolina and the National Institutes of Health describe how reminders of drug use can change specific brain cells responsible for motivation, increasing the desire to seek drugs. Connections between these and other brain cells strengthen because the […]

Lifestyle

Cancer-fighting gene restrains ‘jumping genes’

About half of all tumors have mutations of the gene p53, normally responsible for warding off cancer. Now, UT Southwestern scientists have discovered a new role for p53 in its fight against tumors: preventing retrotransposons, or “jumping genes,” from hopping around the human genome. In cells with missing or mutated p53, the team found, retrotransposons […]

Lifestyle

Eating less suppresses liver cancer due to fatty liver

Liver cancer from too much fat accumulation in the liver has been increasing in many countries including Japan. In order to change this unfortunate state of affairs, it is important to improve the prognosis of non-alcoholic fatty liver disease. Most often the cause of fatty liver is overeating and lack of exercise. Fatty liver is […]